Palpebral oedema associated with sensitization to cobalt in a dental prosthesis.

A 47-year-old woman gave a 1-month history of persistent oedema of the eyelids and lips. There was no apparent relationship to externa] triggering factors, and she liad no known history of sensitization or atopy and no relevant personal or family history. For 1 year she had been wearing a partial removable methacrylate prosthesis (Fig. 1). This was mainly composed of cobalt and chromium (Co: 60%, Cr: 30%, Mn: 5%, Si: 2%. Mo: +. W: +, C: +1. There were no subjective symptoms connected with wearing the prosthesis.